Mutation-induced binding energy change predictions on ACE2:RBD complex, made by the well-known structure-based binding affinity predictors, HADDOCK, FoldX, EvoEF1, SSIPe, and MutaBind2.
==== HOW TO READ THE TABLE ====
1st column: Mutation information, where RBD_N501Y indicates that N501 of RBD is mutated to Y.
Other columns: Predicted binding energy change upon mutation. Lower scores indicate improved binding.
==== HOW TO INTERPRET THE MODELS ====
- To visualize the mutation model generated by each predictor please click on the relevant score (ACE2: blue, RBD: yellow)
- To show or hide reference, please click on “Show Reference/Hide Reference”.
- Please activate “Locate Mutation” to locate the mutation position.
- To get back to the initial view, please refresh the page.
==== REFERENCE ====
This page is a slightly modified version of https://joaorodrigues.github.io/ace2-animal-models/